Press Releases & News
 APRIL 2012 Multi-Parametric Imaging for Stem Cell Research Researchers use the Evolve EMCCD camera to develop a scalable and simple single camera, multi-parametric functional measurement system. Go to page 17 in the electronic edition of the magazine to learn more. |
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 FEBRUARY 2012 Microscopy Mixology - Integrating a hybrid of microscopic methods is a recipe for success in the research environment. Photometrics strives to increase camera resolution and achieve faster speed as the need for imaging larger areas continues to prevail. This Cover Story tells all, read more in the online issue. |
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 FEBRUARY 2012 Live From Photonics West 2012: An Introduction To OEM Imaging Photonics Online interviews Deepak Sharma to learn more about the OEM Imaging, the OEM division of QImaging and Photometrics. |
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 FEBRUARY 2012 Laboratory Equipment Names Photometrics a Finalist for its 2012 Reader's Choice Awards. Now open for voting, the Evolve 128 EMCCD camera is a contender for this award. Winners will be featured in the March 2012 issue of Laboratory Equipment magazine. |
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 JANUARY 2012 HIGH-SPEED IMAGING/ADVANCED MICROSCOPY/OPTOGENETICS: The technology behind the science: Exhibits deliver at Neuroscience 2011 Editor-in-Chief, Barabara Goode, showcases technologies presented at Neuroscience 2011 in Washington D.C. The Evolve 128 EMCCD was mentioned for its speed, that enabled two researchers to measure three parameters simultaneously. |
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 JANUARY 2012 Digital Camera Technologies for Scientific Bio-Imaging. Part 4: Signal-to-Noise Ratio and Image Comparison of Cameras In this article, the last in a four part series, the signal-to-noise ratio (SNR) comparisons begun in Part 3 are expanded with examples of existing cameras in low light and medium-to-high light scenarios. The optical system throughput calculations are combined with collection, conversion, and noise specifications from typical cameras available on the market to generate SNR values at different exposure times and under common user scenarios. Direct quantitative comparisons of image quality are made using SNR graphs and experimental images. |
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 NOVEMBER 2011 Chemists Reveal the Force Within You: New Method for Visualizing Mechanical Forces On Cell Surface A new method for visualizing mechanical forces on the surface of a cell, reported in Nature Methods, provides the first detailed view of those forces, as they occur in real-time. |
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 NOVEMBER 2011 Visualizing mechanical tension across membrane receptors with a fluorescent sensor This report focuses on a fluorescence-based turn-on sensor for mapping the mechanical strain exerted by specific cell-surface proteins in living cells. The sensor generates force maps with high spatial and temporal resolution using conventional fluorescence microscopy. The team demonstrates the approach by mapping mechanical forces during the early stages of regulatory endocytosis of the ligand-activated epidermal growth factor receptor (EGFR). |
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NOVEMBER 2011 Neuroscience 2011: Photometrics Evolve EMCCD Cameras At Neuroscience 2011, M&A Editor Dr. Julian Heath talks to Rachit Mohindra, Associate Product Manager, about the Evolve EMCCD cameras from Photometrics. |
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SEPTEMBER 2011 Digital Camera Technologies for Scientific Bio-Imaging. Part 3: Noise and Signal-to-Noise Ratios The focus of this article reviews noise parameters with an introduction and discussion of various noise sources. In this installment, the noise properties of different scientific cameras are combined with the photon throughput model developed in Part 2 (noted below) to generate signal-to-noise ratio (SNR) profiles for the three sensor types as a function of exposure time. The SNR of an image is a well-accepted metric of image quality and it is used in this discussion to allow quantitative comparison of the sensors. Printer Friendly Version |
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 SEPTEMBER 2011 Imaging Live-Cell Response in Real Time Understanding the molecular mechanisms behind how cells remodel in response to mechanical stimulation is essential to develop therapies for many vascular diseases. An ideal experiment would mechanically stimulate and image live cells in real time. However, the technical requirements of optical microscopy and mechanical stimulation techniques conflict. Learn how Andreea Trache, Ph.D., assistant professor at Texas A&M Health Science Center, solved this issue. |
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 AUGUST 2011 Virtual camera access method library launched Photometrics has announced the release of the latest version of its Programmable Virtual Camera Access Method Library (PVCAM). |
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 AUGUST 2011 Despite competition, the light microscope remains the most important instrument in the laboratory. And it's quickly evolving. Quantitation arrives for light microscopy. Learn how Quant-View imaging, first developed for Photometrics' Evolve 512 EMCCD camera has improved quantitation, reproducibility, and certainty in data comparisons by moving away from arbitrary image intensities that vary from camera to camera and with different gain states, electron microscopy gains, and bit depths. |
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JULY 2011 Powerful Fluorescence Tool Lights the Way to New Insights Into RNA of Living Cells The ability to tag proteins with a green fluorescent light to watch how they behave inside cells so revolutionized the understanding of protein biology that it earned the scientific teams who developed the technique Nobel Prizes in 2008. Now, researchers at Weill Cornell Medical College have developed a similar fluorescent tool that can track the mysterious workings of the various forms of cellular RNA. |
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 JULY 2011 RNA Mimics of Green Fluorescent Protein Discover how researchers can now genetically encode a fluorophore into RNA to track its expression. Learn how the team used the Photometrics CoolSNAP HQ2 to capture the images that support their research. Read the supplemental information pertaining to this research |
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JUNE 2011 Digital Camera Technologies for Scientific Bio-Imaging. Part 2: Sampling and Signal This Part 2 of a 4-part series begins by introducing the detection arm of a fluorescence imaging system and evaluating the standard pixel sizes of three sensor technologies with respect to resolution and sampling. Complementing the analysis is the methodology for calculating the number of photons that will be incident at each pixel of the sensor. Real experimental parameters, such as dye concentration, numerical aperture (NA) and magnification are all considered to determine this photon throughput. Coming soon, Parts 3 and 4 of this series, radiometric throughput will be combined with an analysis of system noise to generate signal-to-noise profiles as a function of exposure time to help select which sensor would be best for a particular application. Printer Friendly Version |
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 JUNE 2011 Biomedical research - an image of the future Scientist James R. Joubert discusses applications of integrated microscopy methods including live cell mechanical stimulation in relation to medical developments. Read this article in the full issue of Laboratory News |
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MAY 2011 How to Build an Integrated Microscopy system for Live Cell Mechanotransduction Studies A new integrated microscopy system allows scientists to simultaneously stimulate and image live cell response in real-time. |
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MAY 2011 Instruments & Systems: Camera Focus The Evolve 128 EMCCD camera boasts features that provide researchers reduced noise and precise, accurate and highly quantitative measurement. |
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 MAY 2011 INSIDE INSTRUMENTATION: The many approaches and applications of biosensing Read this article to learn how a Photometrics customer is using an EMCCD camera to explore how cells react to mechanical stimulation, such as the required expansion and contraction of blood vessels. |
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 MAY 2011 Capturing More in Microscopy Images EMCCDs continue to possess optimal characteristics for high-sensitivity research. See how the Evolve with eXcelon technology is supporting life science research applications that require ultrafast frame rates with extraordinary sensitivity. |
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MAY 2011 Digital Camera Technologies for Scientific Bio-Imaging. Part 1: The Sensors This Part 1 of a four-part series covers the factors to consider in choosing a camera among CCD, EMCCD, and scientific-grade CMOS camera technologies for biological imaging applications. Part 1 focuses primarily on how each sensor works, imaging modes, pixel size, chip size and frame rate. Request a copy of this article |
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APRIL 2011 Imaging Live Cell Response in Real Time Andreea Trache, Ph.D. at Texas A&M Health Science Center designed the first integrated system to use TIRF and fast spinning disk confocal microscopy. Her goal is to study protein dynamics in live cells in response to real-time mechanical stimulation by an atomic force microscope (AFM). Go to pages 22-23 to learn how this ground breaking system incorporates the QuantEM EMCCD camera to support this important research and provide "the best synchronization between the spinning disk and the camera". |
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MARCH 2011 Photometrics in Texas Dr. Andreea Trache has designed one of the first integrated microscopy systems that can simultaneously stimulate and image live-cell responses in real time. Access the full March issue of Microscopy and Analysis Magazine |
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 MARCH 2011 Confocal microscopy gets smaller and faster – and branches out George McNamara, image core manager at the University of Miami's Miller School of Medicine, isn't talking about the importance of the four confocal instruments he manages. Instead, he's talking about tallying photons and the ability to obtain an accurate assessment of the number of fluorescing molecules in ever-decreasing spots in tissue samples. See how improvements in confocal microscopes and novel combinations with complementary microscopy techniques, such as super-resolution, are achieving this to create a fundamental change in the way research is conducted. |
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MARCH 2011 Small Animals, Big Achievements A variety of preclinical imaging applications critically rely on small-animal imaging, with researchers monitoring, for example, changes in organs and tissue in response to physiological or environmental stimuli. Numerous modalities of these applications have been developed to address issues arising from the unique requirements of small-animal imaging. Here is a description of several such approaches to overcome previous limitations, including the use of cameras sensitive to further-penetrating near infrared dye emission and the development of 3D optoacoustic tomography. |
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 MARCH 2011 EMCCD vs. sCMOS for Microscopic Imaging Here we investigate scientific-grade CMOS and EMCCD performance under low-light microscopy conditions by comparing signal-to-noise performance for the two under typical operating conditions. EMCCD sensors have the advantage over recently emerging scientific-grade CMOS sensors in low-light-microscopy imaging applications. |
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SEPTEMBER 2010 Standardized Units for Reproducible Imaging Experiments Reproducible quantitative measurement is a fundamental principle of science. Standardizing imaging data with the photoelectron captures a level of detail currently not seen to help researchers control and compare data for more meaningful conclusions. |
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JULY 2010 Fluorescence Imaging of Cranial Vasculature in Live Animals M. Waleed Gaber, an associate professor at Baylor's College of Medicine and co-director of the small animal imaging facility at Texas Children's Hospital, is investigating factors that influence the health of vasculature surrounding CNS tumors to optimize efficacy and safety of anti-cancer therapies. |
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JUNE 2010 Cover Story: Photometrics Evolve EMCCD Camera Makes 2010 Top Trends for Life Science Research Evolve standardizes the unit of measurement for imaging data, allowing researchers to report live data in photoelectrons. This revolution is supporting scientists by making their research quantifiable and reproducible. |
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 SPRING 2010 Imaging for Cancer Research: Fluorescence Imaging of Cranial Vasculature in Live Animals (page 19) Radiation therapy is one of the most successful treatments for malignant tumors yet there is still work to be done. Dr. Waleed Gaber, associate professor at Baylor's College of Medicine and his team have made a significant discovery and are progressing this area of research using Photometrics imaging solutions. |
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APRIL 2010 LOW-LIGHT IMAGING: Novel back-illuminated CCD enhances low-light-level detection Conventional CCDs come in several forms, each with certain disadvantages for low-light imaging; a new take on back-illuminated technology resolves these issues while maintaining the benefits. |
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MARCH 2010 Integrating Cellular Imaging Data Effectively Advances Allow Researchers to Compare Images Taken at Different Times and Settings |
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 MARCH 2010 Think Big, Work Small: Newest Microscopy Technologies Evolve Camera makes the top of the list with its Photometrics-exclusive technology that measures imaging data in photoelectrons, an absolute and reproducible unit that makes experimental data quantitative and reproducible. |
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MARCH 2010 Measurement Standards/Super-Resolution Microscopy: Quantifying fluorescence EMCCD technology, which revolutionized the life sciences by enabling visualization of low-light events, is quantitative. But EMCCD's standard unit of measure is variable. A non-arbitrary alternative promises better fluorescence microscopy - and better science. |
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 JANUARY 2010 Photonics Media Names Photometrics a Prism Award Finalist for Photonics Innovation for its Evolve Camera View the interview with Rachit Mohindra, Photometrics’ Associate product Manager for the Evolve camera. |
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 JANUARY 2010 Photometrics named top finalist in 2009 Prism Awards for Innovation sponsored by Photonics Media and SPIE |
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 JANUARY 2010 Select Science Reports at ASCB: Novel Method for Quantifying Life Science Imaging |
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 OCTOBER 2009 Advances in EMCCD Technology: Making Imaging Less Arbitrary |
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OCTOBER 2009 A Brave New Image Advancing Fluorescence Imaging |
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 DECEMBER 2009 "Top 10 Innovations" of 2009 Photometrics' Evolve™ EMCCD Camera named one of "The 10 most exciting tools to hit life sciences this year." Guiding Light How to manipulate cellular events with the right light sensing molecule and a flash of light. |
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 OCTOBER 2009 Featured Product |
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 SEPTEMBER 2009 Industry News (.pdf) Industry News (Online version, Page 58) |
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AUGUST 2009 Evolve camera uses photoelectron to measure images Photometrics has introduced the Evolve EMCCD camera, which makes experimental imaging data quantifiable and reproducible by using the photoelectron to scientifically measure an image. |
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SEPTEMBER 2009 Photometrics presents Evolve cameras at Neuroscience Product News Accessories Guide (Page 12) |
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 SEPTEMBER 2009 The Future of Life Science |
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 SEPTEMBER 2009 Watching the Molecules - EMCCD camera lets researchers detect and see things that previously were hard to see. Dr. Deepak Sharma, Sr. Product Manager, Photometrics, discusses issues surrounding current imaging technologies and how the Evolve EMCCD camera helps make bio-imaging less arbitrary, more reproducible. Excerpt from interview with Barry Hochfelder, Editor of Advanced Imaging Magazine and AdvancedImagingPro.com. |
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 AUGUST 2008 Get the Most from Förster Resonance Energy Transfer |
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 APRIL 2006 EMCCD Camera Technology Advances |
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JANUARY 2003 Laurin Publishing awards 2003 Photonics Spectra Circle of Excellence Award to Photometrics for Cascade Camera, first commercially available EMCCD camera for microscopy |
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Photometrics has a rich history of creating new paradigm shifts in the way scientists conduct their research. Clearly the established leader of high-performance cameras, Photometrics consistently develops reliable products that are sought by researchers around the globe.
Photometrics has earned its leadership role with over three decades of strong product design and delivery. The company and its products have achieved multiple awards and continuously set the precedent for how cameras are designed to support and advance life science research.
Photometrics Company Achievements Timeline
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Photometrics releases Evolve™ 128, delivering the industry's highest frame rates and sensitivity for low-light research applications. The release included availability of exclusive eXcelon, a breakthrough back-illuminated CCD and EMCCD detector technology. |
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Photometrics releases Evolve™ 512, creating a paradigm shift in life science research. Researchers gain ability to measure and quantify data in electrons, and create reproducible data in multiple scenarios. |
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Photometrics ships QuantEM, only 16-bit EMCCD scientific camera with bias stability & linearized gain. |
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Photometrics acquires Optical Insights, LLC & integrates multispectral imaging devices (Dual-View, Dual-Cam & Quad-View) into product line. |
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Photometrics develops special camera used by NASA for thermal imaging of space shuttle. |
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Photometrics receives Circle of Excellence Award for Cascade, the world's first EMCCD camera. |
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Photometrics introduces Cascade, the world's first scientific-grade microscopy EMCCD camera. |
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Photometrics introduces its first CoolSNAP camera. |
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Photometrics attains ISO 9001 certification, folding the engineering design process into the quality system. |
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Photometrics ships first Quantix camera. It borrows camera head technology from Series 200, but adds 12-bit digitization up to 5 MHz. |
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Photometrics ships 1st SenSys camera, an inexpensive, self-contained CCD camera utilizing PPD. |
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Photometrics ships 1st “zero footprint” CCD camera with Primary Point Digitization (PPD). |
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Photometrics ships the Star 1 camera system targeted to the astronomy market. Star 1 borrows technology from Series 200, but is simplified to support a single CCD type. |
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Photometrics develops CCD to fiberoptic bonding process; ships 1st fiber-bonded CCD camera. |
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Photometrics develops CCD backthinning process with CCD manufacturers. |
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Dr. Robert Ballard uses Photometrics camera to discover RMS Titanic. |
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Photometrics ships commercially-available, scientific CCD camera, the Model 80A TEC-cooled camera. |
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Photometrics ships first “special” cameras: one-offs typical of high-tech start-ups. Cameras were targeted to the astronomy community. |
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The dawn of high-performance CCD imaging occurs with the establishment of Photometrics in Tucson, Arizona, by Dr. Richard Aikens. |
