Published Research Library
Navigate through this online library resource to see firsthand how Photometrics cameras support the sophisticated imaging requirements for a multitude of cutting edge research applications.
- January 2012
American Journal of Stem Cells
Towards high throughput tissue engineering: development of chitosan-calcium phosphate scaffolds for engineering bone tissue from embryonic stem cells
Camera used: CoolSNAP HQ2
Methods in Molecular Biology
A Live Cell Micro-imaging Technique to Examine Platelet Calcium Signaling Dynamics Under Blood Flow
Camera used: QuantEMMethods in Molecular Biology
Monitoring Integrin Activation by Fluorescence Resonance Energy Transfer
Camera used: QuantEM - December 2011
Nature Methods
Bayesian localization microscopy reveals nanoscale podosome dynamics
Camera used: Cascade II 1024 - November 2011
JCI (Journal of Clinical Investigation)
Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease
Camera used: CoolSNAP HQ2G3 (Genes Genomes Genetics)
Double-Strand Break Repair and Holliday Junction Processing Are Required for Chromosome Processing in Stationary-Phase Escherichia coli Cells
Camera used: CoolSNAP HQ2EMBO Journal (European Molecular Biology Organization)
Cdk1 promotes kinetochore bi-orientation and regulates Cdc20 expression during recovery from spindle checkpoint arrest
Camera used: CoolSNAP HQ2Nano Letters
Dynamic SERS Imaging of Cellular Transport Pathways with Endocytosed Gold Nanoparticles
Camera used: QuantEM
Journal of Immunology
Contact-Dependent T Cell Activation and T Cell Stopping Require Talin1
Camera used: CoolSNAP ES2Scientific Reports
Phosphatidylinositol 4, 5-bisphosphate (PIP2) controls magnesium gatekeeper TRPM6 activity
Camera used: CoolSNAP HQ2BMC Biotechnology
A bacteria colony-based screen for optimal linker combinations in genetically encoded biosensors
Camera used: QuantEMJournal of Stroke and Cerebrovascular Diseases
Survival and Differentiation of Transplanted Neural Stem Cells Derived from Human Induced Pluripotent Stem Cells in A Rat Stroke Model
Camera used: CoolSNAP HQ2PLoS ONE (Public Library of Science)
Dynamic Microtubules Promote Synaptic NMDA Receptor-Dependent Spine Enlargement
Camera used: CoolSNAP HQ2Analytical Chemistry
FRET-based biosensors for multiparameter ratiometric imaging of Ca 2+ dynamics and caspase-3 activity in single cells
Camera used: QuantEMJCB (Journal of Cell Biology)
Sticky/Citron kinase maintains proper RhoA localization at the cleavage site during cytokinesis
Camera used: CoolSNAP HQ2JOVE (Journal of Visualized Experiments)
Study of the Actin Cytoskeleton in Live Endothelial Cells Expressing GFP-Actin
Camera used: CoolSNAP HQ2MBoc (Molecular Biology of the Cell)
The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover
Camera used: QuantEMAmerican Journal of Physiology
Estradiol Attenuates High Glucose Induced Endothelial Nitrotyrosine: Role for Neuronal Nitric Oxide Synthase
Camera used: CoolSNAP HQ2Journal of Neuroscience
The Human Immunodeficiency Virus Coat Protein gp120 Promotes Forward Trafficking and Surface Clustering of NMDA Receptors in Membrane Microdomains
Camera used: QuantEMMicrobes and Infection
A new vesicular compartment in Encephalitozoon cuniculi
Camera used: CoolSNAP HQ2American Journal of Physiology
Estradiol Attenuates High Glucose Induced Endothelial Nitrotyrosine: Role for Neuronal Nitric Oxide Synthase
Camera used: CoolSNAP HQ2
Nature Methods
Visualizing mechanical tension across membrane receptors with a fluorescent sensor
Camera used: Evolve 512 - October 2011
Analytical and Bioanalytical Chemistry
Physisorbed surface coatings for poly (dimethylsiloxane) and quartz microfluidic devices
Camera used: QuantEMLangmuir
QD-Antibody conjugates via carbodiimide-mediated coupling; a detailed study of the variables involved and a possible new mechanism for the coupling reaction under Basic
Camera used: QuantEMCell Metabolism
Genetically Encoded Fluorescent Sensors for Intracellular NADH Detection
Camera used: Evolve 512Journal of Neurophysiology
Inhibitory responses in Aplysia pleural sensory neurons act to block excitability, transmitter release and PKC Apl II activation.
Camera used: QuantEMJournal of Cerebral Blood Flow & Metabolism
Fibrinogen-induced increased pial venular permeability in mice
Camera used: QuantEMJournal of Microscopy
High‐resolution cell outline segmentation and tracking from phase‐contrast microscopy images
Camera used: CoolSNAP HQ2Traffic
Protein trafficking rates assessed by quantum dot quenching with bromocresol green
Camera used: QuantEMPNAS (Proceedings of the National Academy of Sciences)
Shared gene expression in distinct neurons expressing common selector genes
Camera used: CoolSNAP HQ2Current Biology
Rapid De Novo Centromere Formation Occurs Independently of Heterochromatin Protein 1 in C. elegans Embryos
Camera used: QuantEMComputerized Medical Imaging and Graphics
Molecular imaging of small animals with fluorescent proteins: From projection to multimodality
Camera used: CoolSNAP ES2Talanta
A microsecond microfluidic mixer for characterizing fast biochemical reactions
Camera used: Evolve 512Journal of Neuroscience
In Vivo Imaging of Intersynaptic Vesicle Exchange Using VGLUT1Venus Knock-In Mice
Camera used: QuantEMHuman Molecular Genetics
The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins
Camera used: QuantEMBiophysical Journal
Initial Dynamics of Cell Spreading Are Governed by Dissipation in the Actin Cortex
Camera used: Evolve 512 - September 2011
Nature Cell Biology
Adaptive braking by Ase1 prevents overlapping microtubules from sliding completely apart
Camera used: QuantEMNature Communications
Microfluidic quadrupole and floating concentration gradient
Camera used: CoolSNAP HQ2Nature Methods
Light-based feedback for controlling intracellular signaling dynamics
Camera used: Evolve 512Biomedical Optics Express
Quantitative characterization of fluorophores in multi-component nanoprobes by single-molecule fluorescence
Camera used: QuantEMThe Plant Journal
Barley mildew and its elicitor chitosan promote closed stomata by stimulating guard - cell S - type anion channels
Camera used: QuantEMJournal of Nanobiotechnology
Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism
Camera used: CoolSNAP ES2Biotechnology Journal
Translocation of green fluorescent protein by comparative analysis with multiple signal peptides
Camera used: CoolSNAP HQ2 - August 2011
Journal of Trauma
Hypertonic Saline Resuscitation of Hemorrhagic Shock Does Not Decrease In Vivo Neutrophil Interactions With Endothelium in the Blood-Brain Microcirculation
Camera used: QuantEMNature Biotechnology
Quantitative fluorescence imaging of protein diffusion and interaction in living cells
Camera used: QuantEMAmerican Journal of Physiology
G protein-coupled estrogen receptor 1 (GPER)-mediated effects in the rat myometrium
Camera used: CoolSNAP HQ2Biochemical Journal
Divergent effect of mammalian PLC-zeta in generating Ca2+ oscillations in somatic cells versus eggs
Camera used: CoolSNAP HQ2British Journal of Pharmacology
Hydrophobic anions potently and uncompetitively antagonize GABAA receptor function in the absence of a conventional binding site
Camera used: CoolSNAP ES2Biomaterials
Bioimaging and toxicity assessments of near-infrared upconversion luminescent NaYF4: Yb, Tm nanocrystals
Camera used: CoolSNAP HQ2Molecular Pharmacology
Developing Chemical Genetic Approaches to Explore G Protein-coupled Receptor Function-Validation of the use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
Camera used: CoolSNAP HQ2MBoc (Molecular Biology of the Cell)
The filament-forming protein Pil1 assembles linear eisosomes in fission yeast
Camera used: CoolSNAP HQ2JARO (Journal of the Association for Research in Otolaryngology)
TRPA1-Mediated Accumulation of Aminoglycosides in Mouse Cochlear Outer Hair Cells
Camera used: Evolve 512 - July 2011
Microcirculation
Live cell imaging of paxillin in rolling neutrophils by dual-color quantitative dynamic footprinting (DqDF)
Multichannel System used: DV2Diabetologia
Synaptotagmin-7 as a positive regulator of glucose-induced glucagon-like peptide-1 secretion in mice
Camera used: CoolSNAP HQ2Journal of Neuroscience
Netrin-1-Induced Local β-Actin Synthesis and Growth Cone Guidance Requires Zipcode Binding Protein 1
Camera used: CoolSNAP HQ2Biological Chemistry
Dynamics of septin ring and collar formation in Saccharomyces cerevisiae
Camera used: QuantEMJBC (Journal of Biological Chemsitry)
Functional adaptation between yeast actin and its cognate myosin motors
Camera used: CoolSNAP HQ2Circulation
Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes MellitusClinical Perspective
Camera used: CoolSNAP HQ2PLoS ONE (Public Library of Science)
High-Resolution Quantification of Focal Adhesion Spatiotemporal Dynamics in Living Cells
Camera used: QuantEMCellular Physiology and Biochemistry
Homocysteine Induces Phosphatidylserine Exposure in Cardiomyocytes through Inhibition of Rho Kinase and Flippase Activity
Camera used: QuantEMAmerican Journal of Physiology
Reversal of Diabetic Vasculopathy in a Rat Model of Type 1 Diabetes by Opiorphin-Related Peptides
Camera used: CoolSNAP HQ2JCB (Journal of Cell Biology)
Mechanosensitive EPLIN-dependent remodeling of adherens junctions regulates epithelial reshaping
Camera used: CoolSNAP HQ2MBoc (Molecular Biology of the Cell)
MICAL-like1 mediates epidermal growth factor receptor endocytosis
Camera used: CoolSNAP HQ2Current Biology
Identification of mutant phenotypes associated with loss of individual microRNAs in sensitized genetic backgrounds in Caenorhabditis elegans
Camera used: CoolSNAP HQ2Applied Spectroscopy
Multimodal Spectral Imaging of Cells Using a Transmission Diffraction Grating on a Light Microscope
Camera used: CoolSNAP ES2 - June 2011
Cellular and Molecular Bioengineering
Microtubule Tip Tracking and Tip Structures at the Nanometer Scale Using Digital Fluorescence Microscopy
Camera used: CoolSNAP HQ2Journal of Neuroscience
NMDA Receptor Activation Suppresses Microtubule Growth and Spine Entry
Camera used: QuantEMBlood
Bcl-xL inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets
Camera used: QuantEMPNAS (Proceedings of the National Academy of Sciences)
Replication and segregation of an Escherichia coli chromosome with two replication origins
Camera used: QuantEMCell Calcium
Voltage-gated calcium channel types in cultured C. elegans CEPsh glial cells
Multichannel System used: DV2Journal of Cell Science
A calmodulin-related light chain from fission yeast that functions with myosin-I and PI 4-kinase
Camera used: CoolSNAP HQ2JCB (Journal of Cell Biology)
APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage
Camera used: CoolSNAP HQ2Cellular Signalling
Dependence on different Rab GTPases for the trafficking of CXCR4 and CCR5 homo or heterodimers between the endoplasmic reticulum and plasma membrane in Jurkat cells
Camera used: CoolSNAP HQ2PNAS (Proceedings of the National Academy of Sciences)
Chemotactic cell trapping in controlled alternating gradient fields
Multichannel System used: DV2Journal of Micromechanics and Microengineering
Non-intrusive measurements of transitional and turbulent convective heat transfer in a rectangular microchannel
Camera used: CoolSNAP HQ2Journal of Neuroscience
Presynapses in Kenyon Cell Dendrites in the Mushroom Body Calyx of Drosophila
Camera used: CoolSNAP HQ2JBC (Journal of Biological Chemsitry)
Intracellular CB1 cannabinoid receptors are activated by anandamide
Camera used: CoolSNAP HQ2 - May 2011
JBC (Journal of Biological Chemsitry)
Differential Regulation of the Postsynaptic Clustering of γ-Aminobutyric Acid Type A (GABAA) Receptors by Collybistin Isoforms
Camera used: CoolSNAP HQ2PNAS (Proceedings of the National Academy of Sciences)
End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment
Camera used: QuantEMNeurobiology of Disease
Presynaptic silencing is an endogenous neuroprotectant during excitotoxic insults
Camera used: CoolSNAP ES2Journal of Cell Science
Emerin inhibits Lmo7 binding to the Pax3 and MyoD promoters and expression of myoblast proliferation genes
Camera used: Evolve 512PLoS ONE (Public Library of Science)
Microtubules as Platforms for Assaying Actin Polymerization In Vivo
Camera used: CoolSNAP HQ2MBoc (Molecular Biology of the Cell)
Phosphatidylinositol-(4, 5)-bisphosphate regulates clathrin-coated pit initiation, stabilization and size
Camera used: CoolSNAP HQ2Neuroscience
Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice
Camera used: CoolSNAP HQ2PNAS (Proceedings of the National Academy of Sciences)
Targeting and imaging single biomolecules in living cells by complementation-activated light microscopy with split-fluorescent
Multichannel System used: DV2JCB (Journal of Cell Biology)
Meiotic nuclear divisions in budding yeast require PP2ACdc55-mediated antagonism of Net1 phosphorylation by Cdk
Camera used: CoolSNAP HQ2 - April 2011
JTH (Journal of Thrombosis and Haemostasis)
Mechanisms underlying FeCl3-induced arterial thrombosis
Camera used: CoolSNAP HQ2JNC (Journal of Neurochemistry)
Compartment-specific, differential regulation of eukaryotic elongation factor 2 and its kinase within Aplysia sensory neurons
Camera used: QuantEMDevelopment and Stem Cells
Clonal analysis by distinct viral vectors identifies bona fide neural stem cells in the adult zebrafish telencephalon and characterizes their division properties and fate
Camera used: CoolSNAP HQ2Developmental Biology
Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax
Camera used: CoolSNAP ES2Analytica Chimica Acta
Patterning pallet arrays for cell selection based on high-resolution measurements of fluorescent biosensors
Camera used: CoolSNAP HQ2Xenotransplantation
Gene transfer of the adaptor Lnk (SH2B3) prevents porcine endothelial cell activation and apoptosis: implication for xenograft's cytoprotection
Camera used: CoolSNAP HQ2JCB (Journal of Cell Biology)
Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis
Camera used: CoolSNAP HQ2Electrophoresis
Hydrodynamic injection with pneumatic valving for microchip electrophoresis with total analyte utilization
Camera used: CoolSNAP ES2Journal of Neuroscience
Development, Maturation, and Necessity of Transcription Factors in the Mouse Suprachiasmatic Nucleus
Camera used: CoolSNAP HQ2 - March 2011
Journal of Cell Science
Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane
Camera used: CoolSNAP HQ2JCB (Journal of Cell Biology)
Defective nucleotide excision repair with normal centrosome structures and functions in the absence of all vertebrate centrins
Camera used: CoolSNAP HQ2Nucleic Acids Research
Direct measurement of DNA bending by type IIA topoisomerases: implications for non-equilibrium topology simplification
Multichannel System used: DV2Micro Electro Mechanical Systems (MEMS) International Conference
Dual Q-dot transport on microtubule array with polarity defined by nanotracks and microtubule motility control
Multichannel System used: DV2Micro Electro Mechanical Systems (MEMS) International Conference
Microfluidic Western blotting: Cationic surfactant based protein sizing integrated with electrostatic immobilization
Camera used: CoolSNAP HQ2JBC (Journal of Biological Chemsitry)
Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays
Camera used: QuantEMThe Plant Journal
Dynamics of Arabidopsis SUN proteins during mitosis and their involvement in nuclear shaping
Camera used: CoolSNAP HQ2PLoS ONE (Public Library of Science)
An Improved Cerulean Fluorescent Protein with Enhanced Brightness and Reduced Reversible Photoswitching
Camera used: CoolSNAP HQ2Yeast
A novel fission yeast mei4 mutant that allows efficient synchronization of telomere dispersal and the first meiotic division
Camera used: CoolSNAP HQ2MCP (Molecular and Cellular Proteomics)
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae
Camera used: CoolSNAP HQ2 - February 2011
Development
Cilia-driven fluid flow as an epigenetic cue for otolith biomineralization on sensory hair cells of the inner ear
Camera used: Evolve 512RNA
P-body components, Dhh1 and Pat1, are involved in tRNA nuclear-cytoplasmic dynamics
Camera used: CoolSNAP HQ2New Phytologist
Cellular pH measurements in Emiliania huxleyi reveal pronounced membrane proton permeability
Camera used: CoolSNAP HQ2Lab on a Chip
Flexible casting of modular self-aligning microfluidic assembly blocks
Camera used: Evolve 512PNAS (Proceedings of the National Academy of Sciences)
Transient binding of dynein controls bidirectional long-range motility of early endosomes
Camera used: CoolSNAP HQ2EMBO Journal (European Molecular Biology Organization)
Controlled and stochastic retention concentrates dynein at microtubule ends to keep endosomes on track
Camera used: CoolSNAP HQ2JBC (Journal of Biological Chemsitry)
Structural and functional analysis of tomosyn identifies domains important in exocytotic regulation
Camera used: QuantEMCrystal Growth and Design
Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases
Camera used: CoolSNAP HQ2Neuropharmacology
Multiple protein kinases determine the phosphorylated state of the small heat shock protein, HSP27, in SH-SY5Y neuroblastoma cells
Camera used: CoolSNAP ES2JCB (Journal of Cell Biology)
Cadherin exits the junction by switching its adhesive bond
Camera used: CoolSNAP HQ2American Journal of Physiology
Enteric glia promote intestinal mucosal healing via activation of focal adhesion kinase and release of proEGF
Camera used: CoolSNAP HQ2 - January 2011
Methods in Molecular Biology
Toward drug design: recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets
Camera used: CoolSNAP HQ2Endocrinology
Glutamine Triggers and Potentiates Glucagon-Like Peptide-1 Secretion by Raising Cytosolic Ca2+ and cAMP
Camera used: QuantEMGlia
Expression of N‐methyl D‐aspartate receptor subunits in amoeboid microglia mediates production of nitric oxide via NF‐κB signaling pathway and oligodendrocyte cell death in hypoxic postnatal rats
Camera used: CoolSNAP HQ2Journal of Bacteriology
The Coxiella burnetii cryptic plasmid is enriched in genes encoding type IV secretion system substrates
Camera used: CoolSNAP HQ2JBC (Journal of Biological Chemsitry)
Localization of the PIP2 sensor of TRPV1 ion channels
Camera used: QuantEMMBoc (Molecular Biology of the Cell)
The NDC80 complex proteins Nuf2 and Hec1 make distinct contributions to kinetochore-microtubule attachment in mitosis
Camera used: CoolSNAP HQ2Nature Methods
Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans
Camera used: CoolSNAP HQ2JBC (Journal of Biological Chemsitry)
Myosin Va is required for P body but not stress granule formation
Camera used: QuantEMGene
High content imaging-based assay to classify estrogen receptor-[alpha] ligands based on defined mechanistic outcomes
Camera used: CoolSNAP HQ2Biochemical and Biophysical Research Communications
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39
Camera used: CoolSNAP HQ2Journal of Cellular Physiology
Voltage-gated K+ channels play a role in cAMP-stimulated neuritogenesis in mouse neuroblastoma N2A cells
Camera used: CoolSNAP HQ2Journal of Sexual Medicine
Silencing MaxiK Activity in Corporal Smooth Muscle Cells Initiates Compensatory Mechanisms to Maintain Calcium Homeostasis
Camera used: CoolSNAP HQ2MBoc (Molecular Biology of the Cell)
Dynamic and structural signatures of lamellar actomyosin force generation
Camera used: CoolSNAP HQ2
