Prime sCMOS Camera

4.2 Megapixel Scientific CMOS Camera
6.5µm x 6.5µm Pixel Area
72% Quantum Efficiency
Real-time Computational Capabilities

Photometrics Prime and its replacement is the first intelligent Scientific CMOS (sCMOS) camera to incorporate a powerful FPGA-based Embedded Signal Processing™ engine, enabling PrimeEnhance and PrimeLocate, two advanced, real-time processing features. This product is now replaced by our new Prime BSI sCMOS camera featuring 95% QE.

See the Difference

Winner of multiple industry awards, Prime's embedded signal processing engine quantitatively restores images that are hidden in photon noise. Learn more its advanced, real‐time processing features:

Learn more about the Prime family of Scientific CMOS Cameras

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Key Camera Features

Extremely Low Read Noise
- 1.1e- (median)
- 1.3e- (rms)
Fast Frame Rates
- 100 fps
Large Field of View
- 18.8mm sensor diagonal
Optimized Pixel Size
- 6.5 micron pixel pitch
High Quantum Efficiency
- 72% peak QE

Enhanced Dynamic Range
- 30,000:1
- 89.5dB
ESP
- PrimeEnhance
- PrimeLocate
- Multi-ROI (Region of Interest)
Advanced Triggering
- Multiple Expose Out Triggering

Technical Resources

Primary Applications

Super-Resolution Microscopy
Light Sheet Microscopy
High Speed Ratiometric Imaging

TIRF Microscopy
Confocal Microscopy

Image Comparisons

Customer Feedback

The Prime sCMOS camera and the Dual View λ helped us to collect high quality fiber photometry calcium signals at multiple brain areas at the same time.

Han de Jong, Lammel Laboratory, University of California, Berkeley

Customer-Ref-Gene-Expression-Quantitative-Time-Lapse-Microscopye-Univ-Cambridge.php

Christian Schwall, The Locke Group Laboratory, University of Cambridge

The real-time filtering and high frame rates of the Photometrics Prime sCMOS camera enable us to capture even more super-resolution microscopy data and to better characterize variability in the structure of chromatin.

Dr. Kyle M. Douglass, Suliana Manley Lab, Lausanne, Switzerland

Imaging Software and Drivers

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Prime BSI sCMOS | Prime 95B sCMOS Series | Iris sCMOS Cameras | Prime sCMOS