Prime Scientific CMOS (sCMOS) Camera

4.2 Megapixel Scientific CMOS Camera
6.5µm x 6.5µm Pixel Area
72% Quantum Efficiency
Real-time Computational Capabilities

Teledyne Photometrics Prime and its replacement is the first intelligent Scientific CMOS (sCMOS) camera to incorporate a powerful FPGA-based Embedded Signal Processing™ engine, enabling PrimeEnhance and PrimeLocate, two advanced, real-time processing features. This product is now replaced by our new Prime BSI sCMOS camera featuring 95% QE.

The Prime sCMOS camera is an extremely versatile life science imaging solution. It is a high resolution camera with great sensitivity, extremely low noise, high frame rates and impressive dynamic range. The large field of view is ideal for microscopy, maximizing usefulness of the imaging area.

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See the Difference

Winner of multiple industry awards, Prime's embedded signal processing engine quantitatively restores images that are hidden in photon noise. Learn more its advanced, real‐time processing features:

Learn more about the Prime family of Scientific CMOS Cameras

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Key Camera Features

Extremely Low Read Noise
- 1.1e- (median)
- 1.3e- (rms)
Fast Frame Rates
- 100 fps
Large Field of View
- 18.8mm sensor diagonal
Optimized Pixel Size
- 6.5 micron pixel pitch
High Quantum Efficiency
- 72% peak QE
Enhanced Dynamic Range
- 30,000:1
- 89.5dB
ESP
- PrimeEnhance
- PrimeLocate
- Multi-ROI (Region of Interest)
Advanced Triggering
- Multiple Expose Out Triggering

Technical Resources

Primary Applications

Super-Resolution Microscopy
Light Sheet Microscopy
High Speed Ratiometric Imaging
TIRF Microscopy
Confocal Microscopy

Image Comparisons

Customer Feedback

The Prime sCMOS camera and the Dual View λ helped us to collect high quality fiber photometry calcium signals at multiple brain areas at the same time.

Han de Jong, Lammel Laboratory, University of California, Berkeley

We chose the Prime [sCMOS] camera because it provides very high signal sensitivity while minimizing noise. Prime gives us the signal to noise improvement we needed.

Christian Schwall, The Locke Group Laboratory, University of Cambridge

The real-time filtering and high frame rates of the Teledyne Photometrics Prime sCMOS camera enable us to capture even more super-resolution microscopy data and to better characterize variability in the structure of chromatin.

Dr. Kyle M. Douglass, Suliana Manley Lab, Lausanne, Switzerland