The Prime BSI Scientific CMOS (sCMOS) camera delivers the perfect balance between high resolution imaging and sensitivity with an optimized pixel design and near perfect 95% Quantum Efficiency. This 4.2 Megapixel camera with 6.5µm pixels captures highly detailed images at high frame rates, making it the most versatile sCMOS for live cell imaging techniques, including Total Internal Reflection Fluorescence (TIRF), Ratiometric Imaging and Lightsheet microscopy.
Prime BSI delivers the ideal combination of speed, sensitivity, pixel size and resolution for biomedical imaging. The camera offers a unique combination of high QE and 6.5µm pixel size, and is excellent for a wide range of biomedical imaging applications. The Prime BSI is the ideal camera to power the next generation of instrumentation.
The camera has allowed us to acquire images that would otherwise be impossible to obtain, providing a basis for future analysis of how the properties of capillaries, and of red and white blood cells, determine brain blood flow.
Prof. David Attwell, University College London
The high sensitivity and low read noise of the Prime BSI is transformative in these experiments as it enables us to use low levels of excitation power and significantly reduce photo-damage to the tissue.
Dr George Sirinakis, University of Cambridge
The thing that really impressed me is how uniform the sensor is – far fewer hot pixels, noisy pixels and stripes than the last generation of sCMOS cameras. I hardly see a use for EMCCDs anymore.
Dr Seamus Holden, Newcastle University
The Prime BSI, with a 6.5 µm pixel, offers the most flexibility for use with the range of objectives we are using as well as improving the resolution.
Professor Gail McConnell, University of Strathclyde
The increase in QE was huge, and really helped with our application.
Dr. Adam Wexler, European Centre of Excellence for Sustainable Water Technology
Weak fluorescent proteins, which had been impossible to observe with our previous camera, can now be readily visualized.
Jessica Kehrer, Dipl. Ing. & Prof. Friedrich Frischknecht, Heidelberg University Medical School
The direct control of other devices by TTL output allowed reliable high-speed measurements triggered by the camera without a separate real-time controller. The combination of high sensitivity and the ability for fast measurements making use of this sensitivity became very useful.
Prof. Michael J.M. Fischer, Medical University of Vienna
The Prime BSI coupled with our light sheet microscope enables us to capture images every few seconds and still have cells successfully completing mitosis with no ill effects. With our previous instrumentation we were at best able to capture images at minute intervals.
Dr Gary Gorbsky, W.H., Oklahoma Medical Research Foundation
The Prime BSI offers several advantages such as speed, field of view and price when compared to the EMCCD. The service at Teledyne Photometrics is also very good, I was always updated, and my questions were answered quickly, Teledyne Photometrics were really willing to help out.
Dr. Biswajit Pradhan, Delft University of Technology
The low readout noise, high quantum efficiency and large sensor size makes the Prime BSI all we need from a camera.
Redmar Vlieg, Leiden University
The Prime BSI Back-illuminated sCMOS gives EMCCD-level sensitivity at high frame rates and with a very large field of view, speeding up our single molecule tracking acquisition.
Alexander R. Carr, University of Cambridge