EXPRESSHigh Sensitivity sCMOS

The Prime BSI Express Scientific CMOS (sCMOS) is designed on a compact platform optimized for integration and delivers the perfect balance between high resolution imaging and sensitivity with an optimized pixel design, USB 3.2 Gen 2 connectivity and near perfect 95% Quantum Efficiency to maximize signal detection.

  • 95% Quantum Efficiency
  • 1.0e- Read Noise
  • 6.5 µm x 6.5 µm Pixel Area
  • 95 Frames Per Second over USB 3.2 Gen 2

Key Features

Prime BSI Express graph


By bringing the light in from the back of the sensor, photons land directly onto the light receiving surface, maximizing light collecting capability.

The Prime BSI Express combines 95% quantum efficiency with the low 1.0 e- read noise CMS mode to deliver the most sensitive camera based on sCMOS technology at over 40 frames per second.

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Prime BSI Express blueprint

Compact Form Factor

The Prime BSI Express is a compact 78mm x 78mm x 90mm with optimized cooling for the size, ideal for integration into new or existing configurations.

Interface and Integrate

Interfacing and integration is simple with the Prime BSI Express, which uses USB 3.2 Gen 2 for truly uncomplicated connectivity.

Our standard PVCAM driver can be easily installed in Windows operating systems to get the Prime BSI Express running in minutes.

Resolution and Pixel Size

The Prime BSI Express features 6.5 µm pixels, the accepted standard for most live cell applications.

This pixel size provides highly detailed images across the imaging plane and is most suitable for the broadest range of magnifications.

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Superior Background Quality

The Prime BSI Express features Pattern Noise Reduction Technology and Correlated Noise Reduction Technology to ensure that it delivers clean, pattern-free images with minimal pixel defects, delivering improved image quality in low light conditions.

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Family Specifications

Sensor Technology sCMOS
Quantum Efficiency 95%
Pixel Size 6.5 µm x 6.5 µm
Supported Interfaces USB 3.2 Gen 2
Spectrum Capabilities UV (200-400 nm), Visible (400-700 nm)
Near Infrared (700-1000 nm)
Read Noise (median) 1.0 e-
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Camera Models

Sensor Area
Frame Rate
Prime BSI Express
Sensor Area
13.3 x 13.3 mm
18.8 mm diagonal
Frame Rate
43fps @ 16-bit
43fps @ 12-bit
95fps @ 11-bit

Customer Stories

Single-Molecule Imaging

Prof. Madhavi Krishnan University Of Oxford

“With the Prime BSI Express our single-molecule signals are clearly visible, thanks to the minimal camera noise and high signal collection resulting in high sensitivity.”

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DNA-PAINT Super Resolution

Dr. John Danial University of Cambridge

“The Prime BSI Express has excellent noise characteristics and imaging quality, it has become the most robust part of my imaging system!”

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Imaging Photon Bose-Einstein Condensate

Dr. Chris Toebes Twente University, Netherlands

“[The Prime BSI Express] is an ideal camera for this application because of the very low noise combined with the high frame rate.”

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